The Clec9A-RBD project is created on the basis of a DNA vaccine, which, after being injected into a cell, ensures the production of proteins
The drug has recently been successfully tested foranimals. Human trials are just ahead. However, scientists are already saying that this drug is quite promising for itself and can be used in the treatment of people. Its main feature is that it was created using genetic engineering technologies.
The mechanism of work of the drugs is as follows: Once injected into a cell, the vaccine begins to produce pathogenic proteins or antigens, causing an immune response. The antibodies used in the development were used in vaccines against cancer and influenza.
Associate Professor at Yong Lu Ling School of MedicineSilvia Alonso stressed at the National University of Singapore that "the DNA vaccine is very effective in stimulating the immune system, therefore it is especially suitable for the elderly." In addition, according to her, "such genetically engineered drugs can be easily modified depending on the mutation of the virus, so such a vaccine can be effective not only against COVID-19."
The university representative also pointed out that "DNA vaccines are made only once, this is relevant during a pandemic, when millions of doses are required."
Scientists expect clinical trials to begin next year.
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