Scientists have shown what happens in the individual cells of patients who died fromCOVID-19.In the study,
We are grateful to the patients and their families who agreed to donate tissue to COVID-19 research to help better understand this devastating disease.
Aviv Regev, co-author of the study
The team investigated how the SARS-CoV-2 virus affectson the functions of cells and their genetic programs. They used single-cell RNA sequencing data from tissue samples taken from 11 organ systems. Material from the lungs, heart, liver and kidneys was used to build a comprehensive "cell atlas" of hundreds of thousands of individual cells showing how COVID-19 can lead to multiple organ failure and death.
The cell atlas team is located infree and open access for study by other scientists. The authors of the project also created a biobank of 420 samples from deceased patients, which can be used for other COVID-19 research.
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