To observe the fast signals of neurons in the brain of fish, scientists began to use techniques under
Now scientists from the European laboratoryMolecular Biology (EMBL) have combined artificial intelligence (AI) algorithms with two advanced microscopy techniques to reduce image processing time from days to seconds, while maintaining image clarity and accuracy. The results of the study appeared in the journal Nature Methods.
“In this development, we were able to combine the best oftwo worlds, - notes Niels Wagner, one of the two leading authors of the article, a graduate student at the Technical University of Munich. “AI has allowed us to combine different microscopy techniques so that we can acquire images very quickly without compromising on quality.”
Researchers capture first 3D images inside a living mouse
To take advantage of everyoneapproach, EMBL researchers have developed an approach that uses brightfield microscopy to image large 3D specimens and plane illumination microscopy to train AI algorithms, which then create an accurate 3D image of the specimen.
“If you imagine algorithms that createimage, you need to verify that these algorithms create the correct image, '' explains Anna Kreshuk, EMBL team leader, whose team brought machine learning expertise to the project. In the new study, scientists used light sheet microscopy to make sure the AI algorithms were working. This distinguishes our research from what has been done in the past. "
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