The likelihood of early death from a stroke depends on the blood type

Scientists from the University of Maryland School of Medicine analyzed data from 48 different genetic

studies on the development of ischemic stroke at a young age. The results showed that people with blood group II (A) have a 16% higher risk of early development of the disease.

In their work, the researchers conducted a meta-analysis of the data,collected in previous studies that collectively included 17,000 stroke patients and a control group of almost 600,000 people who had never experienced a stroke. Comparison of genetic data has shown a relationship between the early onset of stroke, occurring before age 60, and the region of the chromosome that includes the gene that determines the blood type.

Scientists have found that people with early strokemore often had II blood group (A), and less often the most common I blood group (O). This ratio was carried out in comparison with people with a late stroke, and with people who have never encountered this disorder. At the same time, people with blood group III (B) more often than the average for the population encountered both early and late development of a stroke.

After adjusting for gender and other factors,which could affect the results, the scientists found that blood type II increases the risk of stroke before age 60 by 16%, and group I reduces it by 12%.

The authors of the study note that it is not yet clear what explains such a relationship between blood type and circulatory disorders in the brain. They plan to continue researching this dependency.

We still don't know why the blood type is Aposes a higher risk, but it probably has something to do with clotting factors such as platelets and cells that line blood vessels, as well as other circulating proteins, all of which play an important role in the development of blood clots.

Stephen Kittner, MD, professor of neurology at the University of Maryland School of Medicine and study co-author

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Cover image: University of Maryland School of Medicine