The project, which has received ethics approval from the UK government, will study how many
In human trials, volunteers deliberatelyinfected with a pathogen in a controlled environment. Researchers can then closely examine disease progression or possible treatments with a level of detail largely unavailable in traditional studies.
Proof test capabilityCOVID-19 has sparked controversy. Some question the ethics of exposing volunteers to the risk of contracting a relatively new pathogen, the long-term effects of which are not fully understood. For this trial, the promise of an accelerated study outweighs the risks for participants, according to UK regulators.
Within a month, researchers hope to recruitup to 90 healthy volunteers aged 18 to 30 who have not contracted the coronavirus. People under the age of 30 tend to have a lower risk of hospitalization or death than older people, but serious illness can still occur.
Volunteers in isolated hospital roomswill be exposed to varying levels of the original variant of the coronavirus circulating since March 2020. The volunteers will then be monitored around the clock, allowing researchers to determine the minimum dose of coronavirus needed to start infection.
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