On behalf of the head of the Ministry of Health, the Russian consortium for sequencing the genomes of coronaviruses carried out
The data obtained indicate a low rate of variability of the coronavirus and the effectiveness of Russian vaccines against COVID-19, noted the Influenza Research Institute, under whose leadership the study was conducted.
An analysis of changes in the structure of the surface protein S (spike protein) showed that the majority of viruses (63.4%) differed from it by only one amino acid residue.
In the overwhelming majority of cases,mutation D614G, characteristic of the representatives of clade G and its derivatives GH and GR, which have a global distribution. In turn, 33.3% of circulating viruses carry 2–3 substitutions, and only 2.9% have 4 or more substitutions.
The specialists noted that monitoring of such strains continues on an ongoing basis.
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