A method has been developed for the interaction of nanoparticles with human biomolecules

Nanoparticle-based drugs are likely to be more effective than current treatments.However

There are complexities due to which the applications of these particles are limited to research laboratories.

In order to solve this problem, the authors of the work presented a unique combination of microscopy techniques that allow for a more detailed look at the biological effects that occurwhen using nanoparticles. 

The researchers' methods allowed them to see important differences between particles exposed to and not exposed to human plasma. 

It's all about the so-called biological bits:they attach to the nanoparticle, creating a coating called a corona (not to be confused with a new type of coronavirus). This crown contains information on how nanoparticles interact with patient molecules.

The authors of the work believe that these particles canwork as diagnostic tools, not drugs. Rather than trying to cure diseases with nanomedicine, the particles are well suited for early detection of diseases, in particular cancer and neurodegenerative diseases.

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