Scientists from Baylor College of Medicine, Stanford School of Medicine and other institutions have determined
Experts from Baylor College of Medicine,Stanford School of Medicine and other institutions were able to identify a molecule that is produced in the body of mice during exercise, and also suppresses appetite and helps with obesity. Scientists wanted to understand how exercise affects the body at the molecular level.
Jonathan Long, Yun Xu with colleaguesanalyzed the composition of the blood plasma of mice that were previously engaged on a treadmill. It turned out that the Lac-Phe molecule was the most significant. When obese mice were given a high dose of this molecule, their food intake was reduced by about 50 percent within 12 hours, and if they received Lac-Phe for 10 consecutive days, they had a decrease in overall food intake, weight, and improved glucose tolerance. .
In addition, experts identified the enzymeCNDP2. This substance was found to be involved in the creation of Lac-Phe. Mice that lacked CNDP2 did not lose as much weight when exercising.
Scientists also noticed that the level of Lac-Phe inplasma levels after exercise are greatly elevated in racehorses and humans. Among the most effective exercises for weight loss, sprinting exercises come first, followed by weight training, and after them – endurance exercises.
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