According to a new study, viral DNA in the human genome, inserted from ancient infections, works like
Previous studies have shown that fragmentsAncient viral DNA, known as endogenous retroviruses, in the genomes of mice, chickens, cats and sheep provide immunity against modern viruses that arise outside the body, blocking their entry into host cells. Although this study was conducted with human cell culture in the laboratory, it shows that the antiviral effect of endogenous retroviruses likely works in humans.
Scientists used computer genomics toscanning the human genome and cataloging all potential retroviral envelope protein coding sequences that could retain receptor binding activity. They then performed additional tests to determine which of these genes were active, that is, expressing retroviral envelope gene products, in certain types of human cells.
Ultimately, they found clear evidence of expression. And many of them are expressed in early embryos and germ cells, and some in immune cells during infection.
This work will help in future research.Scientists will be able to find a pool of natural antiviral proteins that will provide treatment without autoimmune side effects. It also reveals the possibility of a genome protection system. In other words, the human genome contains a reservoir of proteins that can block a wide range of viruses.
Read more:
Archaeologists have officially confirmed the legends from the Bible
It turned out what happens to the cells of the body when the heart dies
Starlink signal hacked to be used as an alternative to GPS