Biologists at Duke University study cells and what happens inside them. These processes correspond to growth and
As part of the study, scientists were able to lookinside the cells of a developing fruit fly. Its growth process is coordinated by a fine network of protein fibers just beneath the cell surface, each 10,000 times thinner than a human hair. They help the cells maintain their shape by acting as reinforcement in concrete, scientists explain.
Photo: Molecular Biology of the Cell (2022). DOI: 10.1091/mbc.E21-11-0537
But unlike reinforcement, these fibers are constantlymove and change. Usually such parts are too small. Observations with conventional microscopes, which can only take a few images per second or are too out of focus, are not revealing.
So scientists at Duke University used ultra-high-resolution fluorescence microscopy to trace individual fibers at nanoscale resolution.
Video: Duke Research Blog
As part of this type of observation, researchersThey hope to better understand how wound healing occurs in humans and how abnormalities develop in children with birth defects such as cleft lip and spina bifida.
The results of the study are detailed in an article published in the journal Molecular Biology of the Cell.
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