Cancer cells can "break" through the protective membranes of the mammary glands

The primary tumor may form inside the mammary duct, where cancer cells are confined

basement membrane.Breast tumor cells are larger than the pores in the membranes, so they must rupture to spread to other tissues. It was previously thought that malignant cells use enzymes to dissolve membranes. It was discovered that breast cancer cells open the canal walls with the help of special protrusions. They then penetrate surrounding tissue and can travel further through blood vessels to spread throughout the body.

The observation used a modifiedscientists fluorescent microscope, which carried out video filming of cells at the nanoscale. This made it possible to measure the strength of impulses emanating from cancer cells.

"Previous studies have measured movementcell protrusions over longer periods of time, but our study showed that a lot can happen in just 15 minutes. Our methods provide more accurate computational data. I believe that technological developments will ultimately contribute to the development of preclinical research,” said Juho Pocki.

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