In a new work, biologists decided to test whether a new type of coronavirus can integrate into human DNA. For
HEK 293 is a cell line derived from human embryonic kidneys. Due to the ease of cultivation and transfection, it has become widespread in modern cell biology.
In addition, it is widely used in the biotechnological and pharmaceutical industries as a producer of therapeutic proteins and viruses for gene therapy.
We examined assumptions that humancells and the molecular mechanisms operating within them convert COVID-19 RNA into DNA, causing irreversible mutations, conducted DNA sequencing and found no evidence of COVID-19 in DNA.
Geoff Faulkner, professor and molecular biologist at the Queensland Brain Institute
As a result, it turned out that SARS-CoV-2 issingle-stranded polyadenylated RNA-beta-coronavirus, which does not encode reverse transcriptase (RT) and, therefore, is unable to induce mutations that allow it to integrate into human genomic DNA during its life cycle.
According to the authors, one of the reasons for such a study was a large number of misconceptions around a new type of coronavirus and vaccination.
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