Coronavirus Genome Changes Cause Pandemic Surge

Despite the fact that SARS-CoV-2 has only 15 genes, it constantly mutates. Most of these changes do not have

very important, but some affect the transmission speed.

The authors of the new work initially analyzedgenomes of 150 strains of SARS-CoV-2. They classified outbreaks into stages: index (no outbreak), rise, exponential rise and fall. The ease of transmission of a virus is determined by the R value, or reproductive number, where R is the average number of new infections caused by each infected person.

They combined all this information into a metric underthe name GENI to identify the genome of the pathogen. Comparison of the GENI scores with the epidemic phase showed that the increase in genetic variability occurred just before the increase in incidence.

When, at the end of March, the British governmentintroduced a lockdown, the number of new cases stabilized, but mutations continued to grow. This shows that measures such as banning gatherings and social distancing are effective in controlling the spread of the disease amid the rapid evolution of the virus.

Read more

The most stormy place on Earth: why Drake Passage is the most dangerous route to Antarctica

New uranium compound breaks record for anomalous conductivity

Evolutionary error: which organs in the human body work illogically