The Mango system consists of an RNA aptamer that binds tightly and specifically to a fluorescent dye.
RNA molecules modified in such a way that they contain an aptameric magnet are isolated from non-target parts of the cell - this greatly facilitates the study of RNA molecules under a microscope.
Mango NABSA kits can be used to test for coronavirus, which is a positive-strand RNA virus, the study authors noted.
“Cell regulation occurs at the RNA level.For a long time, the focus was on protein, but it is RNA, not protein, that regulates the vast majority of cellular processes. Mango's technology is state of the art, and the development of effective cancer drugs and tests for various viral diseases requires better imaging techniques to quickly study how cells work in detail."
Peter Unrau, lead author of the study
Now in 160 countries there are more than 244thousand cases of infection with this infection. 90% of all cases occur in five countries - China, Italy, Iran, Spain and Germany. At the same time, in China, where the virus came from, there is a significant reduction in the epidemic. Since the end of 2019, 9.8 thousand people have died from coronavirus infection, more than 86 thousand people have recovered. In Russia, there are now 199 patients with coronavirus infection, of whom nine were cured, and one patient died.
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