Fecal transplant can reverse aging

Scientists from the Quadram Institute and the University of East Anglia conducted a new study on mice. During

experiments, they found that transplanting fecal microbiota from young to old individuals can reverse the signs of aging in the gut, eyes and brain.

In a reverse experiment, microbes from old mice caused inflammation in the brains of young recipients and depleted a key protein needed for normal vision.

The results of a new study show that gut microbes play a role in regulating some of the detrimental effects of aging.

Community of bacteria in the human intestineknown as the gut microbiota, has long been linked to human health. In fact, changes in the types and behavior of bacteria, viruses, fungi and other microorganisms in the human gut can be associated with most diseases.

For example, these changes in the composition of the microbiotacan occur as a person ages and is associated with age-related diseases such as inflammatory bowel disease, cardiovascular, autoimmune, metabolic and neurodegenerative diseases.

The team will then work to determinehow long these beneficial effects may last, as well as identifying beneficial components of the young donor's microbiota and how they affect organs other than the gut. And then they can begin to investigate whether this method will work in humans.

Fecal microbiota transplantation (FMT), alsoknown as “stool transplantation”, “fecal transplant”, “fecal microbiota transplant”, “fecal bacteriotherapy”, “fecal therapy” is the process of transplanting intestinal bacteria and bacteriophages contained in the stool of a healthy person or several healthy people to a recipient. The FMT procedure is a process of forced artificial restoration of the normal balance of intestinal microflora by introducing the entire complex of “healthy” living bacteria and their bacteriophages. They are usually found in a suspension or in the filtrate of a healthy donor's stool solution.

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