A heart attack occurs when blood flow to the heart suddenly stops. This disease can sometimes
Signs of heart disease can appear in the mostdifferent places of the body. These include the ears and a condition known as Frank's sign, named after the man who first noticed the fold, physician Sander Frank.
Frank first drew attention to this phenomenon when he noticed it in patients with chest pain and blockage of the coronary arteries. Frank's sign is also known as diagonal earlobe crease.
Some studies show that thisthe crease is associated with an increased risk of heart disease. One theory is that Frank's sign is related to the loss of elastin and elastic fibers, a process that damages blood vessels in people with coronary heart disease.
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