The study found that exposure to propofol affects the process by which neurons
Vesicles are relatively small intracellular organelles, membrane-protected bags in which nutrients are stored or transported.
Biologists have noticed that the movement of vesicles of twoknown kinesins, kinesin-1 and kinesin-3, decreased in cells that were exposed to propofol. This delay results in not enough protein being delivered to the axons.
Propofol is the most popular drug for generalanesthesia. Despite its frequent clinical use, exactly how it works is poorly understood. That's why scientists conducted an experiment. “The mechanism of action of propofol is not fully understood,” the scientists write. “What we found surprised us: propofol altered the movement of vesicles in living neurons.”
It is noteworthy that most studiesdevoted to the anesthetic mechanism of propofol, focus on its interaction with the ion channel - GABA receptors, which, when activated, inhibits neurotransmission.
Now scientists have shown that transportationThe vesicle also provides the anesthetic effect of propofol. The discovery has important implications for human health and may lead to the development of more effective anesthetics.
Read more:
A massive impact from a space object triggered the Earth's magnetic field
Scientists Confirm Alternative Gravity Theory: Why It Changes Physics
Pig heart beats slower after transplant to human
</ p>