Researchers from the University of South Australia have developed technology to combat persistent sick leave.
Scientists have developed a method of antimicrobialphotodynamic therapy using liquid crystal lipid nanoparticles of gallium protoporphyrin (GaPP-LCNP). The active substance is applied to the wound in the form of a lotion. When exposed to laser light, GaPP creates reactive oxygen species that serve as an alternative to conventional antibiotics.
The authors of the work note that the existing methodssubstances with poor solubility are used. In their technology, they have concentrated on using food grade lipids to create a compound with increased solubility and antibacterial properties.
The principle of the technology. Image: Muhammed Awad et al, Pharmaceutics
The study showed that the finished moleculestarget multiple bacterial cells at the same time, preventing bacteria from adapting and becoming resistant. In a series of experiments, researchers have shown the effectiveness of a new treatment method to combat two of the most common and dangerous types of nosocomial infections. At the same time, skin cells involved in the wound healing process showed increased vitality, and antibiotic-resistant bacteria were completely destroyed, scientists say.
Staphylococcus aureus (Staphylococcus aureus) and Pseudomonas aeruginosa are among the deadliest superbugs in the world. Over a million people are estimated to die from antibiotic-resistant bacteria.
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