Recent technical advances have opened up a number of interesting possibilities in the fight against hair loss, from
What is the cause of baldness
Led by Chinese scholarsResearchers at Zhejiang University set out to develop new treatments for the most common condition associated with hair loss: male and female pattern baldness, also known as androgenetic alopecia. Scientists have tried to solve this problem by focusing on the underlying mechanisms that they believe are behind it, namely oxidative stress and circulatory disorders.
This is due to the combination of the accumulation of reactiveoxygen species in the scalp, which kill cells that promote new hair growth, and a lack of blood vessels around the follicles to provide them with nutrients and essential molecules. Thus, the team hopes to develop a two-pronged approach to androgenetic alopecia, and their solution builds on previous research done on liver damage and Alzheimer's disease.
What is the essence of the invention
In previous experiments, scientistshave developed nanoparticles containing the chemical element cerium, which have been shown to be effective in reducing oxidative stress seen in these diseases. Adapting this technology to combat hair loss would mean developing a way for nanoparticles to penetrate the skin, leading the researchers to the idea of using a microneedle patch for delivery.
Patches have been shown to stimulate growthnew blood vessels around hair follicles, however, a patch containing cerium nanoparticles has shown several advantages. The recipients showed clear signs of new hair development, such as earlier skin pigmentation and higher concentrations of certain compounds. These mice also had fewer oxidative stress compounds in the skin.
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