Microneedle patch cuts hair loss by increasing blood flow to follicles

Recent technical advances have opened up a number of interesting possibilities in the fight against hair loss, from

solutions for topical use containingstem cells, to 3D printing hair farms and growing hair using the patient's own cells. Scientists from China are proposing another option, which uses an absorbable microneedle patch to stimulate hair growth, and the technology has proven to be highly effective in treating hereditary baldness in mice.

What is the cause of baldness

Led by Chinese scholarsResearchers at Zhejiang University set out to develop new treatments for the most common condition associated with hair loss: male and female pattern baldness, also known as androgenetic alopecia. Scientists have tried to solve this problem by focusing on the underlying mechanisms that they believe are behind it, namely oxidative stress and circulatory disorders.

This is due to the combination of the accumulation of reactiveoxygen species in the scalp, which kill cells that promote new hair growth, and a lack of blood vessels around the follicles to provide them with nutrients and essential molecules. Thus, the team hopes to develop a two-pronged approach to androgenetic alopecia, and their solution builds on previous research done on liver damage and Alzheimer's disease.

What is the essence of the invention

In previous experiments, scientistshave developed nanoparticles containing the chemical element cerium, which have been shown to be effective in reducing oxidative stress seen in these diseases. Adapting this technology to combat hair loss would mean developing a way for nanoparticles to penetrate the skin, leading the researchers to the idea of ​​using a microneedle patch for delivery.

Patches have been shown to stimulate growthnew blood vessels around hair follicles, however, a patch containing cerium nanoparticles has shown several advantages. The recipients showed clear signs of new hair development, such as earlier skin pigmentation and higher concentrations of certain compounds. These mice also had fewer oxidative stress compounds in the skin.

Source: acs

Images: rob3000 / Depositphotos

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