Ministry of Health: three trials of coronavirus are undergoing clinical trials in Russia

The document states that three drugs against coronavirus are currently being tested in Russia - umifenovir, remdesivir

and favipiravir. However, the document does not say where these drugs are tested and whether there are any results from these experiments.

In addition, coronavirus infection in Russiatreated with drugs that are effective among patients with SARS associated with SARS-CoV and MERSCoV coronaviruses. These drugs include a combination of lopinavir and ritonavir, chloroquine, hydroxychloroquine, and interferon preparations.

Usually a combination drug lopinavir andRitonavir is used to treat HIV infection and is a viral protease inhibitor. Studies have shown that it is also able to inhibit the activity of coronavirus protease. This kit has found its application in the treatment of MERS-CoV infection and is today used to treat infection caused by the new coronavirus SARS-CoV-2.

Although in a study in which199 patients participated, a set of lopinavir and ritonavir did not show statistically significant efficacy compared to standard therapy, this combination remains in the clinical recommendations of many countries to combat COVID-19.

Interferon is also used in combination with lopinavir and ritonavir. It has antiproliferative, antiviral and immunomodulating activity.

Now in 175 countries there are more than 549thousand cases of infection with this infection. 90% of all cases occur in seven countries - the USA, China, Italy, Spain, Germany, Iran and France. At the same time, in China, where the virus came from, there is a significant reduction in the epidemic. Since the end of 2019, 24 thousand people have died from coronavirus infection, more than 124 thousand people have recovered. In Russia, there are a total of 1063 patients with coronavirus infection, three patients died, 45 were cured.

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