The new development, the authors emphasize, will be relevant for people who cannot get the vaccine, as well as
Vaccines work by stimulating the adaptive immune systemsystem, after which it creates antibodies against diseases and viruses. By taking a small piece of a virus that does not cause infection, scientists can train the adaptive immune system to recognize specific viruses. Once the adaptive immune system is trained, it can respond more quickly to subsequent exposures to a specific virus.
The innate immune system, however, is moreuniversal. It identifies any pathogen it may encounter, be it bacterial, viral or fungal. One of its main functions is the production of cytokines, which can be called the first line of defense upon contact with the virus. Cytokines also alert the immune system to the presence of the virus and trigger the adaptive immune system.
The intracellular protein STING works assignaling for the immune system. Once it is triggered, the production of the cytokine interferon begins. This activity stimulates the adaptive immune system to fight infection.
STING's adversary is diABZI-4, which could potentially wake up the immune system, giving it a boost to fight pathogens.
immunostimulating properties of diABZI-4 can also be used as an antiviral drug. It is already being tested as a cancer immunotherapy.
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