A group of researchers from Oxford University conducted a study and found out exactly how high
According to the International Diabetes Federation,More than half a billion people around the world live with diabetes, the majority of people suffering from type II diabetes. The disease is characterized by hyperglycemia, in which high levels of glucose circulate in the bloodstream.
A previous study showed that T2DMappears as a result of an unbalanced diet and lack of physical activity. Chronically high sugar consumption leads to the development of the disease, which impairs the body's ability to release insulin. This hormone is known to regulate blood glucose levels.
But how does chronically high blood glucose levelsdamages beta cells that produce insulin - unknown. Elizabeth Haythorne, one of the lead authors of the new study, found that chronic hyperglycemia can damage beta cells. She wanted to understand exactly how this happens.
Scientists have conducted several studies on animalsand cultured cells. It turned out that it is not glucose itself that disrupts the function of beta cells that produce insulin, but the products that are formed in the process of glucose metabolism. Researchers still don't know which glucose metabolites trigger the process. What is clear is that inhibition of glucose metabolism maintains insulin production even when blood glucose levels are high.
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