Scientists from NUST MISIS and specialists from the State Scientific Center for Applied Microbiology and
Scientists note that there is now an increase inantibiotic consumption. In order to reduce the amount of consumption and prevent the consequences, the authors turned to antimicrobial nanohybrids. The main advantage of such drugs, according to scientists, is a significant reduction in the dose of the antibiotic, which reduces the load on the body and slows down the development of resistance in microbes.
So scientists created nanoparticles made on the basis of hexagonal boron nitride with silver particles: they showed high bactericidal and antifungal activity.
h-BN nanoparticles with a size of 100 nm are obtainedchemical vapor deposition, then silver particles are deposited on them by ultraviolet decomposition of silver nitrate. The cavities of the nanoparticles are saturated with antibiotics, which, after administration of the drug, gradually enter the body over nine days.
Kristina Gudz, Engineer, Laboratory of Inorganic Nanomaterials, NUST MISIS
The researchers claim that thenanohybrids are capable of destroying bacterial and fungal populations with a much lower active substance than antibiotics currently on the market. Sometimes the difference reaches 6-7 times.
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