New technology turns a conventional light microscope into an ultra-high-resolution device. In him
The technology is simple: you need to place the sample on the material, and then under a conventional microscope.
Light microscopes are useful for imagingliving cells, but they cannot be used to see something smaller. Conventional light microscopes have a resolution limit of 200 nanometers. Any objects closer than this distance will not be observed as separate objects. And while more powerful instruments such as electron microscopes exist, they cannot be used to observe living cells. For them, the samples must be placed in a vacuum chamber.
The technology consists of a glass slidemicroscope covered with a special material. It consists of alternating layers of silver and silica glass several nanometers thick. As light passes through it, wavelengths shorten and scatter.
Artistic visualization of new technologyultra-high resolution microscopy. Animal cells (red) are placed on a glass slide covered with multilayer hyperbolic metamaterial. Nanoscale structured light (blue) is generated by the metamaterial and then illuminates living cells. Credit: Yeon Yoo Lee
Using this material, a conventional light microscope can be used to obtain images of living subcellular structures with a resolution of up to 40 nanometers.
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