Patch finds signs of cancer using laser pulses

Engineers have created an electronic patch that tracks biomolecules in deep tissues. According to

developers, it can be used to detect life-threatening conditions and formations, including organ dysfunction and malignant tumors.

New electronic patch created by employeesUniversity of California at San Diego. This is an improved version of the patch that was created in 2018 . It used ultrasonic waves to continuously monitor the thickness of pulsating blood vessels to analyze blood pressure in real time.

Now scientists have developed a monitoring versionblood perfusion is its passage through tissue. This bodily function is key to healthy tissue function and the transport of oxygen and nutrients. When it is difficult, it indicates severe organ dysfunction and an impending heart attack. At the same time, abnormal accumulation of blood may indicate hemorrhage or the development of malignant tumors. Thus, continuous monitoring of blood perfusion will help detect these life-threatening conditions.

New patch developed in CaliforniaUniversity of San Diego, adheres comfortably to the skin and can be used to detect a number of diseases. Credit: Xiaoxiang Gao/Jacobs School of Engineering/UC San Diego

Scientists have focused on a biomoleculehemoglobin in deep tissues. “The amount and location of hemoglobin in the body provides important information about blood perfusion or accumulation in specific locations,” explained study co-author Sheng Xu. — Our device has great potential. It will be useful for careful monitoring of high-risk groups.”

The fin itself is flexible and comfortableadheres to the skin. It features arrays of laser diodes and piezoelectric transducers in a soft silicone polymer matrix, sending pulsed lasers into the tissues below. Biomolecules in deep tissues absorb optical energy, which leads to the emission of acoustic waves through the tissue. Piezoelectric transducers accept them. They are then processed in an electrical system to restore the spatial representation of the emitting waves of biomolecules.

In testing, the system created three-dimensional maps of hemoglobin in tissues located several centimeters below skin level, with submillimeter spatial resolution.

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