The authors of the new work examined antibody levels in people whose data was contained in PubMed and Google Scholar since
We found one or more studies oneach of these viruses, providing information about the drop in IgG antibody titers to the S protein, nucleocapsid protein, or whole virus lysate after infection. <…> We then searched PubMed and Google Scholar using the terms “phylogeny,” “phylogenetics,” “evolution,” and “phylogenomics” in combination with terms from our previous search for articles that included phylogenetic relatedness information.
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As a result, the authors got severaldata sets on how immunity resisted reinfection with six coronaviruses from 128 days to 28 years after the first infection. This made it possible to identify typical profiles of falling antibody titers and the risk of recurrence.
Based on the results of the work, scientists determined that whenIn endemic conditions—the constant presence of a particular infection in a certain area—re-infection with SARS-CoV-2 can occur from three to 63 months after peak antibody values. On average - after 16 months.
It is also noted that this period of timeturned out to be almost two times shorter than for other human coronaviruses. For example, for SARS-CoV, recurrence can occur from four months to six years, and for HCoV-OC43 from 15 months to 10 years. From 31 months to 12 years for HCoV-NL63 and from 16 months to 12 years for HCoV-229E.
Our assessment strongly objects toclaims that herd immunity can defeat the epidemic, or that long-term risks of morbidity and mortality can be reduced without vaccination. Relying on herd immunity without widespread vaccination threatens millions of lives and entails high rates of reinfection and death. For areas with low vaccination rates, our analysis confirms the need for sustained measures such as social distancing, proper indoor ventilation and wearing masks to avoid re-infection.
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