In their work, the team of scientists described in more detail the entire structure of the SARS-CoV-2 genome inside the host cell. For
The various functional parts of the genome mustwork together despite the great distance between them. New data on the structure of the virus show how it lives and actively reproduces.
The RNA genome of coronaviruses is about three times larger than the average viral RNA genome. It's huge!
Omer Ziv, a doctor from the Gurdon Institute in the UK
The researchers assumed that the workgenes of the coronavirus has a profound effect on their replication and the production of viral proteins. But until recently, there were no tools to fully map these interactions. Now that this work has been studied, it may be possible to create more effective drugs to target them.
Coronaviruses have a special place wherethe ribosome stops only in 50% of cases. In another 50% of cases, a unique form of RNA causes the ribosome to produce additional viral proteins. The study mapped the RNA structure to understand the strategies by which coronaviruses make their proteins.
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