Scientists have discovered a new method of imaging in cell observation

In their research, the scientists combined two microscopy techniques.One

It was used to observe the surface of cells, and the other was used to study the molecular activity inside.Fluorescence microscopy allowed researchers to look inside individual cells, and ion conduction scanning microscopy created 3D topographic images of cell membranes.Simultaneous observation provides a more holistic view of the connections between phenomena occurring simultaneously in the cell.

Cells, a fundamental component of livingorganisms take part in a number of complex biological phenomena. The more opportunities researchers have to study these phenomena in detail, the easier it is to understand the types of disorders and diseases in order to develop effective treatments.

“The cell membrane is where it isinteracts with his environment, says Samuel Mendes Leitan, one of the study participants. - It is here that many biological processes and morphological changes take place, for example, during a cellular infection. Our new observation system allows us to analyze the molecular structures inside the cell and determine exactly how they interact with membrane dynamics. We can track dynamics in detail over time ranges from subseconds to days with continuous nanoscale imaging. ”

EPFL scientists believe their new system canused to monitor phenomena such as cell motility, differentiation and intercellular communication. This opens up many new areas of research in the biology of infections, immunology, and neurobiology.

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