Typically, bioengineered skin helps burn victims. However, it is only produced in the form of flat
Flat sheets of bioengineered leather are suitable fortransplants to relatively flat parts of the body, but are not suitable for, for example, hands. In such cases, you usually have to sew several sheets together to fit all the nooks and crannies - this is a very labor-intensive process.
Scientists from Columbia Universityhave developed a more convenient alternative. To start, they used a 3D scan of the part of the body that needed a graft. They then used a 3D printer to create a life-size, hollow, permeable model of the part.
Then biologists seeded it with fibroblast cellsskin (form connective tissue), collagen (gives structure) and keratinocyte cells (make up the outer layer of skin). The inside of the model was filled with nutrient medium.
As soon as the cells turned into realthe skin was removed from the model and “put on” the damaged part of the body. The whole process took about three weeks. How much is required to grow ordinary flat sheets of leather.
In the laboratory, scientists checked3D grafts made from human skin cells on the hind legs of mice. The operation itself took about 10 minutes, and the grafts were completely integrated into the surrounding skin of the animal after four weeks. It turned out that solid grafts are mechanically stronger than if they were made from several sheets sewn together.
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