Scientists from Duke University showed a video showing chaotic movements in real time.
In order to reproduce themselves, viruses mustpenetrate cells, but how exactly they do this remains unclear. This is because they are captured before they get inside. In this environment, they move much faster, and the viruses themselves are relatively tiny compared to the cells they infect.
Therefore, in the new study, employeesDuke University have developed a new imaging method. It was called microscopy of three-dimensional tracking and visualization (3D-TrIm, English 3D Tracking and Imaging Microscopy).
Essentially, it works by combining two microscopes intoone. The first uses a laser to pinpoint the positions of the virus at a rate of 1,000 times per second. The virus is made visible by a fluorescent label attached to it. The laser excites it, causing it to glow so that it can be observed under a microscope.
Second microscope takes 3D imageslarger cells around the virus, creating a real-time 3D video of its movements of the virus as it moves into the cell. The video above shows one such example.
The new method will help to learn more about how viruses infect cells. But before that, it is necessary to improve the technology, for example, to find a way to make viruses glow longer.
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