The alpha strain of coronavirus has the N501Y mutation, present in a key contact region of the spike protein. He
The beta strain of coronavirus is one of several variants of SARS-CoV-2 that is of particular concern. It is more contagious and dangerous compared to the usual version.
The authors of the new work found out how actively the antibodies from the Sputnik V vaccine bind to the widespread new variations of the coronavirus.
Certain variations of coronavirus can be avoidedthe action of antibodies from the vaccine, and the nature of this maneuver is different. At the same time, we emphasize that the Sputnik V vaccine will protect patients from severe forms of COVID-19 and when infected with these virus strains.
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During the work, the authors collected blood serum from12 residents of Argentina, who at the beginning of 2021 received two doses of the Russian vaccine, in order to understand how actively the antibodies from these samples will combine with literally dummies of SARS-CoV-2, which contained the proteins of the coronavirus envelope.
It turned out that the South African strain or beta, as well as some variants of other strains of SARS-CoV-2 with the E484K mutation, reduce the effectiveness of the vaccine.
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