We inherit all our genes from our parents. There are several genes that behave differently in offspring, in
It is known that the proteins contained in the egg (proteins,which we get from our mom) help protect these imprinted genes during early embryonic development. Therefore, these egg proteins can have either long-term or short-term effects on the health of the embryo.
Professor Blevitt's research team studied the SMCHD1 protein, which uses epigenetic modification to turn off certain genes.
We investigated whether the maternal SMCHD1 proteinbe transferred into a newly formed embryo; if so, how does this affect the expression of imprinted genes. Using advanced microscopy to track the fluorescently labeled version of SMCHD1, we saw that the maternal SMCHD1 protein persists in embryos for at least five cell divisions.
Marnie Blewitt, Professor
The study revealed that there is a certaina period of time, it falls on early embryonic development, during which the maternal SMCHD1 protein can stop the expression of target genes.
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