Scientists of the Research School of Chemical and Biomedical Technologies of Tomsk Polytechnic
To conduct the study, the scientists used200 breeding cows on farms in the Tomsk and Novosibirsk regions suffered from serous mastitis, a disease caused by Escherichia coli. Researchers compared the effectiveness of a combined-action veterinary antibiotic and a drug made from silver nanoparticles.
The control group of cows received an antibiotic,the main one is a drug based on silver nanoparticles. An analysis of bacteria isolated from milk showed that the sensitivity of bacteria to 31 types of antibiotics decreased by 27.3% when treated with a traditional drug, and increased by 21.2% after treatment with silver nanoparticles.
This allows us to conclude that nanoparticlessilver restores the sensitivity of microflora to antibiotics, which subsequently determines their effectiveness when used in both animals and humans.
Alexey Pestryakov, Professor, Research School of Chemical and Biomedical Technologies, Tomsk Polytechnic University
The researchers found that silver nanoparticlesreduce the formation of biofilms by groups of bacteria, reduces their ability to attach to living cells. This may lead to an increase in the action of antibacterial agents under the influence of silver nanoparticles, the scientists add. The results of the work can be used in the development of prophylactic agents based on silver nanoparticles or additives to antibiotics for effective therapy.
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