The Lancet confirms the effectiveness of Sputnik Light: everything you need to know about the vaccine

The Sputnik Light vaccine has confirmed its effectiveness in an authoritative international journal, but it has

their contraindications, as well as side effects, which we will discuss in more detail.

What has become known after the published results of a vaccine study?

The Lancet has an article on efficiencysingle-component vaccine "Sputnik Light". The study involved 110 volunteers 18–59 years old from St. Petersburg. First, they were tested for antibodies to a new type of coronavirus. 14 people had them, and 96 did not. According to this principle, two groups were formed.

One injection of the vaccine was enough to causeimmune response in volunteers assigned to the group without antibodies. As a result, 96 people (100%) developed specific antibodies in their blood serum as early as 42 days after the administration of Sputnik Light.

In volunteers who had antibodies in advance,the immune response was detected already after 10 days. The authors of the study measured antibodies on the 10th, 28th and 42nd days after the vaccine was administered. At all three stages, the average antibody titers were higher in those volunteers who were already immunocompromised before the study.

This information confirms that sufficientmaintain antibodies and be revaccinated with a single dose of vaccine. Earlier it became known that after inoculation with the second component "Sputnik V", the amount of antibodies does not increase. A similar study was published for Pfizer.

Who is Sputnik Light suitable for?

According to the head of the Ministry of Health Mikhail Murashko,The Sputnik Light vaccine was developed for people who have already suffered a new coronavirus infection or received two doses of the Sputnik V two-component vaccine. He noted that the vaccine can also be used for primary vaccination of certain categories of the population. Sputnik Light cannot be used for people over 60 years old, added Murashko.

Doctor of Biological Sciences Alexander AlekseevichChepurnov noted that Sputnik Light is also suitable for primary vaccination "out of necessity." The same idea was confirmed by Anatoly Davidovich Alshtein, Doctor of Medical Sciences, and added that Sputnik Light is similar in function and operation to the first component of the Sputnik V vaccine, after which antibodies appear in about 3-4 weeks.

The vaccine also has contraindications, for example,hypersensitivity to any of the components, a history of severe allergic reactions, acute infectious and non-infectious diseases (vaccination is carried out 2-4 weeks after recovery or remission), it is still impossible to vaccinate with mild ARVI, acute infectious diseases of the gastrointestinal tract (vaccination is carried out after temperature will return to normal), as well as pregnancy, breastfeeding or under 18 years of age.

Also, with caution, suggest vaccinatingpatients with endocrine diseases, chronic liver and kidney disease or hematopoietic system, also with epilepsy or other problems with the central nervous system and if a person has acute coronary syndrome, acute cerebrovascular accident, myocarditis, endocarditis, pericarditis. And also for patients with autoimmune diseases and malignant neoplasms.

Where can Sputnik Light be implanted?

At the end of July 2021 it became known thatOne third of Russian regions received the vaccine: Sputnik Light was delivered to 35 constituent entities of the Russian Federation, excluding Moscow and the Moscow region. The list of regions where large deliveries reached were: Krasnodar Territory, Dagestan and Tatarstan, Rostov, Chelyabinsk, Sverdlovsk, Leningrad, Irkutsk and Nizhny Novgorod Regions. 10-18 thousand doses were sent there.

But at the end of October it turned out that in the regionsthe demand for the vaccine has grown significantly and there has been a shortage of Sputnik Light. It was recorded in the Voronezh region, Kurgan, Vologda region, Krasnoyarsk Territory and St. Petersburg. Such interest in "Sputnik Light" is associated with the fact that the vaccine is one-component and immediately after vaccination you can get a QR code that allows you to visit public places.

An unofficial site has appeared on the Internet, where a map of places where you can vaccinate with "Sputnik Light" has been published.

What are the reviews about the Sputnik Light vaccine?

According to research, as well as information fromself-observation diaries, side effects are usually mild or moderate. They occur in the first two days after the introduction of the vaccine and end within the next three days.

Most often, patients reported flu-likea syndrome with chills, fever, joint pain, muscle pain, general malaise and headache, as well as painful sensations at the injection site and swelling.

Vaccinated people are recommended to take painkillers, antipyretic and anti-inflammatory drugs with an increase in temperature and a pronounced local reaction.

Following the publication in The Lancet of research onthe Sputnik Light vaccine, the safety of the drug is more likely to be confirmed. Note that a mistake can occur in scientific research at any level, but an authoritative international journal is one of the most reliable guarantees.

Despite this, mass vaccination may be less successful if the pace of production and delivery of Sputnik Light is reduced. Especially during the period of increasing restrictions in the regions.

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