During a bacterial infection, the body uses chemoattractants, molecules that attract
Scientists have used Staphylococcus aureus,which is known for drug resistance. They attached a chemoattractant to the popular antibiotic vancomycin. Their interaction increased the number of immune cells. “We have been working on using 'hybrids' of a dual-acting antibiotic and chemoattractant that improve neutrophil recruitment and increase the chances of killing the bacteria,” said Dr. Jennifer Payne, lead researcher at the Monash Institute for Discovery of Biomedicine.
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Scientists applied the basics of microfluidics. They engineered the infection on a chip to track the appearance of a person's immune cells. Scientists have observed in real time how the interaction of vancomycin and chemoattractant eliminatesStaphylococcus aureus.
Researchers are looking for partners to continue clinical trials to develop an antibiotic strategy in intensive care settings to protect the most vulnerable patients.
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