A team of researchers from the Cold Spring Harbor Laboratory (CSHL) in New York has figured out how to stop the growth
The BRD8 protein mechanism affects the functioninganother protein, P53, which suppresses the development of tumors in the human body. The authors describe BRD8 as the "Achilles' heel" of glioblastoma, and P53 as the body's natural defense mechanism against cancer.
They suggest that turning off BRD8 could reactivate P53 and stop the growth of glioblastoma.
According to researchers, it is deadlysince the tumor is usually detected at a late stage. It grows quickly and disrupts brain function. Typically, glioblastoma is treated with surgery followed by chemotherapy or radiation therapy.
The problem is that cancer cells takevarious forms. Even in the same patient, tumors show different morphological characteristics. As a result, this heterogeneity of cells makes it difficult to treat glioblastoma even with therapy.
Glioblastoma is one of the most dangerous types of cancer,affecting the brain and spinal cord. More than 240,000 people die each year from cancer of the nervous system, and in most cases, glioblastoma is the leading cause of death. The tumors spread quickly and cause very painful cramps and headaches. There is no known 100% effective treatment.
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