A clinical study conducted by a scientist from the Australian Cardiac Research Institute
As the gold standard for diagnosisrejection biopsy is used. During this procedure, a tube is inserted into the jugular vein through which surgeons remove several samples of heart tissue. Patients typically need up to 12 such procedures during the first year after transplantation. The results are used to evaluate the effectiveness of immunosuppressive treatments used to prevent rejection.
In his work published in the journalAmerican Heart Association Circulation, researchers suggest using MRI to analyze the level of cardiac edema to identify signs of possible rejection without invasive intervention.
Scientists tested their technology in a hospitalSaint Vincent. During the work, 401 MRI and 354 biopsies were performed in 106 patients. A randomized trial has shown that the new technology is safe and as effective as a biopsy. At the same time, in patients who did not undergo invasive intervention, there was a decrease in the frequency of hospitalizations and infections.
“This new virtual biopsy takes lesstime, is non-invasive, more economical, does not use radiation or contrast agents, and most importantly, patients prefer it,” says Andrew Jabbur, co-author of the study.
In the future, the scientists plan to expand the study to test the effectiveness of the technology in heart transplantation in children, as well as to diagnose inflammation of the heart that is not associated with transplantation.
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